Common bathroom item that could help reduce the spread of coronavirus

Common bathroom item that could help reduce the spread of coronavirus

Researchers from Cardiff University’s School of Medicine, along with five other universities globally, claim oral rinses are an “under-researched area of major clinical need”.

A Welsh university has called for urgent research into whether mouthwash could be effective in reducing the spread of coronavirus.

Coronavirus, referred to in the universities’ study as Sars-CoV-2, is described as an “enveloped virus” with an outer fatty (lipid) membrane.

But the scientists claim there has been “no discussion” about the potential role of damaging this membrane as a possible way to inactivate the virus in the throat.

They say previous studies have shown that agents commonly found in mouthwashes – such as low amounts of ethanol, povidone-iodine and cetylpyridinium – could disrupt the lipid membranes of several enveloped viruses.

It is not yet known whether this could also be the case for this new coronavirus.

The researchers assessed existing mouthwash formulations for their potential ability to disrupt the Covid-19 lipid envelope – and suggested that “several” deserve clinical evaluation.

Their research was published on Thursday in the academic journal, Function.

The authors state: “We highlight that already published research on other enveloped viruses, including coronaviruses, directly supports the idea that further research is needed on whether oral rinsing could be considered as a potential way to reduce transmission of SARS-CoV-2.”

They said research to determine the potential of this approach could include evaluating existing – or specifically-tailored – formulations of mouthwash in the lab and then in clinical trials.

Professor Valerie O’Donnell, co-director of Systems Immunity Research Institute at Cardiff University

Lead author Professor Valerie O’Donnell, co-director of Cardiff University’s Systems Immunity Research Institute, said:”Safe use of mouthwash – as in gargling – has so far not been considered by public health bodies in the UK.

“In test tube experiments and limited clinical studies, some mouthwashes contain enough of known virucidal ingredients to effectively target lipids in similar enveloped viruses.

“What we don’t know yet is whether existing mouthwashes are active against the lipid membrane of Sars-CoV-2.

“Our review of the literature suggests that research is needed as a matter of urgency to determine its potential for use against this new virus.

“This is an under-researched area of major clinical need – and we hope that research projects will be quickly mobilised to further evaluate this.”

However, Professor O’Donnell warned that people should continue with social distancing and strict hand hygiene.

She added: “Mouthwash has not been tested against this new coronavirus yet.

“People should continue to follow the preventive measures issued by the UK Government, including washing hands frequently and maintaining social distance.

“This study suggests further clinical studies could be worthwhile based on the theoretical evidence.”

Cardiff University’s School of Medicine carried out the review alongside the universities of Nottingham, Colorado, Ottawa, Barcelona and Cambridge’s Babraham Institute.

Expert virologists, lipid specialists, microbicide and healthcare experts were all involved in the study, while industry partners provided global formulation information.

Professor O’Donnell was made a Fellow of the Academy of Medical Sciences on Wednesday.

Collection of African women fashion styles and accessories

Post a Comment

0 Comments